Paediatric Asthma: Causes, Symptoms, and Treatment Options

Paediatric Asthma

What is paediatric asthma?

Asthma is a long-term (chronic) condition where your child’s lungs can get irritated by being exposed to various triggers such as cold weather, pollen, etc. When this happens, the inside of the airways swell up, and produce more mucus and the muscles around the airways get tight making it difficult for you to breathe¹

Asthma often starts when kids are young, and it's more common in boys than girls.

Fortunately, there are effective treatment options available to manage asthma symptoms and improve their quality of life.

How common is asthma in childhood?

Asthma is a common disease in children. Recent data shows that worldwide,

Around 9-10% of Children aged 6-14 worldwide have asthma

The total burden of asthma in India is 34.3 million

Accounting for 13.09% of the global burden.³

The occurrence rate is notably higher among boys and in urban areas.⁵

The number of children affected by this condition is going up over time.^4,6,7

Symptoms of paediatric asthma

When kids have asthma, they might experience-:

Recurrent coughing.

Have ongoing wheezing (a high-pitched whistling sound made while breathing), especially when sleeping or triggered by activities like crying or laughing.

Worsening of asthma symptoms at night or early in the morning.

Tightness in their chest or trouble breathing, such as feeling out of breath or breathing quickly.

Feeling tired from not sleeping well.

Act cranky or easily upset.

These symptoms can vary from being not too bad to very severe. Sometimes, worsening symptoms can lead to severe health risks, indicating a worsening of the condition. During this time, symptoms such as increased wheezing, shortness of breath, coughing (especially at night), lethargy, reduced exercise tolerance may occur. If your child shows any of these signs, it is crucial to seek medical help immediately.⁴

Triggers of paediatric asthma

Viral Infections
Pathogenic agents like viruses can cause infections in the lung passages. Viral infections can cause the airways to become inflamed, leading to wheezing and possibly developing into asthma.⁹

Allergens & Irritants
Your child may have allergies to things like dust and pollen grains. Other factors include dust mites, pet dander, etc., which can trigger their symptoms. Certain environmental triggers, like air pollution, gases, strong odours from coils, cooking smells, sprays, or smoke, can irritate your child's airways and worsen their symptoms.

Exercise
Physical activities (strenuous play or exercise) can sometimes cause wheezing, coughing, and a feeling of chest tightness in children with respiratory issues due to the narrowing of airways.

Stress & Emotions
When your child feels stressed, it can cause shortness of breath and exacerbate their symptoms.^1,4,10

Risk factors of childhood asthma

Factors that could raise the likelihood of your child developing asthma include:

Viral infections can significantly impact both the development and exacerbation of asthma. If your child gets viral infections a lot, it might increase the chances of them developing asthma.^9,18

Having previous allergic reactions, i.e., food allergies.

A family history of asthma or allergies.

Living in areas with a lot of pollution.

Being overweight.

Having ongoing respiratory issues, such as rhinitis.

Maternal obesity and weight gain during pregnancy heighten the likelihood of asthma in offspring.

Being around tobacco smoke during pregnancy and childhood raises the risk of developing asthma.^4,11,12

Paediatric asthma diagnosis and tests

Diagnosing asthma in children can be tricky, especially when they're young. Asthma symptoms can resemble those of other childhood illnesses, occasionally resulting in inaccurate or mistaken diagnoses.

To diagnose asthma, your child's doctor may use several methods:

Physical examination and review of medical history

Allergy Tests
(Skin prick or blood tests, especially if there's a history of allergies)

Lung function tests
(Spirometry measures how well the lungs are working in children aged ≥5)

Chest X-ray
(To examine the condition of the lungs)

In children <5 years of age, the doctor might recommend a trial of asthma medication for a minimum of 2-3 months to see if the symptoms improve.^{4, 13}

Patients with close family members, like a parent or sibling with asthma or allergies, are more likely to suffer from it.¹

Preventing asthma worsening

To prevent asthma attacks, planning carefully and avoiding things that can trigger them is essential. Here are some tips:

Reduce exposure to asthma triggers
Try to keep your child away from things that worsen asthma, such as allergens (house dust mite, furred pets, pest rodents, cockroaches, mold, and pollen) or irritants (car exhaust fumes, smoke, or strong smells).

No smoking around your child
Tobacco smoke is a considerable risk for childhood asthma, so keep your child away from it.

Treatment as prescribed
Adherence to doctor-prescribed medications.

Encourage physical activity
If your child's asthma is well controlled, regular exercise can improve their lung function. Always consult a doctor to ensure the exercise routine is safe and suitable for your child's condition.

Regular check-ups
See your child's doctor regularly. Don't ignore signs that their asthma might not be well controlled.

Maintaining a healthy weight
Being overweight can exacerbate asthma and lead to additional health issues. Regular monitoring is essential.⁴

Paediatric asthma treatment

How doctors handle your child's asthma at the beginning depends on how bad it is.

Treating asthma involves two main steps: stopping symptoms from occurring and dealing with asthma attacks if they do occur.

The type of medicine your child needs depends on their age, what symptoms they have, what triggers their asthma, and what works best to keep them in check.15

Asthma medications fall into two categories:

Maintenance medications

These must be taken regularly, regardless of symptoms, to prevent and control symptoms, reduce airway inflammation, and decrease the risk of exacerbations.
Inhaled corticosteroids (ICS) are the most commonly prescribed maintenance medications. They reduce chronic inflammation and prevent airway narrowing and shortness of breath.
They are taken particularly by inhalation and can be used to treat mild to severe asthma.
If asthma isn't well controlled with these, the dose can be increased or combined with other medications.
Overall, ICS are safe and should be reviewed on how well it's working as the symptoms of children can change over time to time and need to be checked and adjusted to manage asthma effectively.

Reliever medications

Also known as rescue medications, these are fast-acting medications used as needed to relieve acute symptoms.
They provide quick relief during asthma flare-ups and helps in reducing breathing difficulties during exercise.
Reducing the need for reliever medications is a key goal in asthma management.
Using your reliever more than twice a week indicates poor asthma control.
In such cases, long-term controller medications should be taken regularly to address the underlying airway inflammation.13,14,16

Treatment types

Inhaled medications can be delivered using different types of devices like dry powder inhalers (DPI), pressurized metered dose inhalers (pMDI) and breath actuated inhalers (BAI). These devices help deliver drugs directly to the lungs.
DPIs contain the drug in a powder form and the child has to inhale deeply and forcefully to get the medicine into the lungs.

pMDIs contain the drug along with a propellant in a liquid or gaseous form and the child has to inhale the medicine slowly and deeply. Add-on devices like spacers or masks may be beneficial for patients who are unable to use their pMDIs correctly.
BAIs are new-age inhalers that automatically releases the drug when the child breaths in.

In patients who are unable to use the inhalers, nebulizers, which convert the drug in a liquid form into a mist that can be used as a treatment option

Asthma action plan

It helps you recognise severe asthma attacks or worsening symptoms.

It helps you understand which medication to administer or how to initiate the treatment.

It guides you on when to contact the doctor or seek emergency help by providing telephone, emergency, or hospital contact details¹⁷

Reference

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